For children with serious health conditions, such as cancer and other chronic diseases, maintaining good nutrition can be a significant challenge.1 They may experience difficulty getting the nutrition they need due to a variety of factors related to their disease. Depending on the condition this may be caused by:2-4
Increased energy
expenditure
Altered metabolic
function
Malabsorption of
nutrients due to
vomiting or
diarrhoea
Inflammation
Difficulty eating
due to dysphagia
In many cases, a child’s inadequate nutritional intake may be linked to reduced appetite as a result of their condition and/or treatment – such as chemotherapy.2,3,5-10
Nausea and
vomiting
Gastrointestinal
problems
Changes in sense
of taste or smell
Pain and fatigue
Effective nutritional management is important to support a child’s growth and development.11 Without appropriate nutrition support, children with disease-related malnutrition can be significantly impacted by:7
Increased risk of
infection
Reduced tolerance
to treatment
Increased
frequency and
length of hospital
stay
Decreased quality
of life
Increased
mortality risk
APPETITE DECLINE IN RESPONSE TO THERAPEUTIC INTERVENTIONSChildren with cancer and other chronic diseases may receive different therapeutic interventions, depending on their condition, that can impact the GI tract. For example, children undergoing chemotherapy may experience gastrointestinal (GI) symptoms resulting from GI toxicity induced by the treatment itself.10 Chemotherapy targets rapidly dividing cells, including both cancer cells and healthy cells in the GI tract, leading to side effects such as inflammation of the mucosal tissues (mucositis) which can cause pain when swallowing.12-13
Symptoms such as these are associated with a decline in appetite, meaning important nutrients are lost and not replaced,7 contributing to the child's undernutrition.10,14
START SMALL, GROW TOGETHERChildren with a reduced appetite or who are unable to consume large volumes of food may benefit from nutritional support to ensure they receive the essential nutrients they need - in the form of energy-dense, low-volume (or ‘compact-style’) oral nutritional supplements (ONS) designed specifically for children.11
Compact-style ONS play a key role in nutrition support strategies and can significantly increase:11
Compliance
Energy intake
Protein intake
Body weight
The use of compact ONS may also promote greater capacity to gradually consume more foods.11 While food is the most important source of nutrition, drinking a compact ONS before their meal can help them meet age appropriate nutrient intake, and has been shown to improve appetite.11
After a bottle of PaediaSure Compact, most children were just as hungry and ate just as much as usual:*15
· 68% of children said they felt just as hungry as before, or even hungrier15
· 80% of parents said their child ate just as much, if not more, after drinking PaediaSure Compact15
PaediaSure Compact has been specially formulated for children at risk of malnutrition who may benefit from a smaller volume of feed.
Nutritionally complete
19.4% fats as MCTs, supporting improved tolerance
16% more protein than other compact paediatric ONS†
Suitable for kosher, halal, vegetarian‡ and gluten-free diets
3 great-tasting16-17 flavours with a consistency that’s “just right”§18
In a crowded field of nutrition options, finding the right product can be challenging.
PaediaSure Compact stands out from the crowd with its unique formulation and benefits, helping you make an informed prescription choice that meets the highest standards for your patient's health and growth.
PER 125 ML SERVING | PAEDIASURE COMPACT | FORTINI COMPACT MULTI FIBRE19 | ALTRINI COMPACT FIBRE20 |
|---|---|---|---|
ENERGY | 301 kcal | 300 kcal | 300 kcal |
PROTEIN | 8.4 g | 7.1 g | 7.5 g |
PROTEIN: ENERGY RATIO | 11.2% | 10% | 10% |
SUGARS | 5.38g | 20.3g | 9.4% |
FATS AS MCTS | 19.4% | 0% | 0% |
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Footnotes:
MCT, medium chain triglycerides
ONS, oral nutritional supplement
*In a satiety study
†Compared with Fortini Compact Multi Fibre.
‡Vitamin D is synthesised from cholesterol, extracted from the grease in wool sheared from live sheep. Most manufacturers use vitamin D from this source, which is approved by the Vegetarian Society
§ Independent taste research involving 23 children found that 83% of children scored the thickness of PaediaSure Compact as ‘just right’.
References:
1. NHS 2023. Malnutrition. Available online: https://www.nhs.uk/conditions/malnutrition Last accessed February 2024.
2. Jeong SJ. Korean J Pediatr 2011;54(7):277-281.
3. Puoti MG. Köglmeier J. Nutrients 2023;15:62.
4. Knebusch N et al. Nutrients. 2023;14:4142.
5. Bischoff SC et al. Clin Nutr 2020;39:632e653.
6. Balestrieri P et al. Nutrients 2020;12(2):372.
7. Triarico S et al. Eur Rev Med Pharmacol Sci. 2019;23(3):1165-1175.
8. Romano C et al. J Pediatr Gastroenterol Nutr 2017;65(2):242-264.
9. Blackburn C et al. Annual Report of the Chief Medical Officer 2012; 9.
10. Akbarali HI et al. Adv Cancer Res. 2022;155:131-166.
11. Hubbard GP et al. Eur J Pediatr. 2020;179(9):1421-1430.
12. Deleemans JM et al. BMC Cancer. 2019;1243
13. NHS. Mucositis. Available online: https://www.nhs.uk/conditions/mucositis/
14. Pedretti L et al. Nutrients. 2023;15(3):710.
15. Data on file. Abbott Laboratories Ltd., 2017 (PaediaSure Compact satiety claims research)
16. Data on file. Abbott Laboratories Ltd., 2017 (Sensory research and evaluation:PaediaSure Plus vs. PaediaSure Compact).
17. Data on file. Abbott Laboratories Ltd., 2017 (Sensory research and evaluation: PaediaSure Compact banana flavour and PaediaSure Compact strawberry flavour).
18. Data on file. Abbott Laboratories Ltd., 2017 (Palatability and taste research).
19. Fortini Compact Multi Fibre datasheet [Accessed November 2024].
20. Altrini Compact Fibre datasheet [Accessed January 2025].
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