Muscle loss is associated with morbidity and mortality in older orthopaedic patients1
Age, illness, immobility and poor nutrition contribute
to muscle loss2-5
Muscle loss can increase the risk of falls and fractures, which can lead to hospitalisation6,7
Muscle loss is accelerated in hospitalised older adults which increases the risk of complications and death8,9
30% increased risk of death following a 20% loss of lean body mass9
MUSCLE LOSS CAN ALSO LEAD TO:
Physical disability5,10
Impaired immune function9
Poor balance and increased falls5,10
Compromised wound healing10
Poorer quality of life10
Increased length of hospital stay10
Adequate protein intake is essential to help minimise declines in strength and function.11
Acts directly on muscle to promote its function through specific vitamin D receptors found on muscle cells.12
ß-hydroxy-ß-methylbutyrate (HMB)
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1. Ekinci O et al. Nutr Clin Pract 2016;31(6):829–835.
2. Wilkinson DJ et al. Clin Nutr 2018;37(6):2068–2075.
3. Baier S et al. JPEN 2009;33(1):71–82
4. Flakoll P et al. Nutrition 2004;20(5):445–451.
5. Cruz-Jentoft AJ et al. Age Ageing 2019;48:16-31.
6. Mithal A et al. Osteoporos Int 2013;24(5):1555–1566.
7. Clynes MA et al. Calcif Tissue Int 2015;97(5):445–452.
8. Hegerova P et al. Nutrition 2015;31(1):166–170.
9. Demling RH. Eplasty 2009;9:e9.
10. Argiles JM et al. JAMDA 2016;17:789-796.
11. Deutz NE et al. Clin Nutr 2014;33(6):929–936.
12. Wagatsuma A and Sakuma K. Biomed Res Int 2014:121254.
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